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ACTIVE LEARNING TEMPLATE: Medication STUDENT NAME MEDICATION Loratadine CATEGORY CLASS REVIEW MODULE PURPOSE OF MEDICATION Ex
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Answer #1

Expected pharmacological action: It is an antihistamine

Therapeutic use: It is advised for running nose, sneezing, watery eyes, rash on skin, hives, and any other allergic symptoms.

Complications:

  • Bradycardia/Tachycardia
  • Headache
  • Drowsiness
  • Dry mouth
  • Hypo/hyperactive

Medication administration:

Adult: 10mg oral OD

Pediatrics: 2-5 yrs: 5mg orally OD

6 yrs or more: 10mg orally OD

Precautions to be taken:

  • If the dose is missed at any reason, skip the missed but do not repeat the missed dose.
  • Follow the doctor’s precautions
  • Inform the doctor in case of pregnancy
  • Inform doctor in case of allergy towards the medicine

Interactions:

Histamine discharge is a key go between in unfavorably susceptible rhinitis and urticaria. Therefore, loratadine applies it's impact by focusing on H1 histamine receptors.

Loratadine ties to H1 histamine receptors found on the outside of epithelial cells, endothelial cells, eosinophils, neutrophils, aviation route cells, and vascular smooth muscle cells among others. H1 histamine receptors fall under the more extensive umbrella of G-protein coupled receptors, and exist in a condition of balance between the dynamic and latent structures. Histamine authoritative to the H1-receptor encourages cross connecting between transmembrane spaces III and V, balancing out the dynamic type of the receptor. Then again, antihistamines tie to an alternate site on the H1 receptor supporting the dormant structure.

Henceforth, loratadine can all the more precisely be delegated a "reverse agonist" instead of a "histamine rival", and can forestall or lessen the seriousness of histamine interceded indications

Contra indications:

  • Hypersensitivity
  • Itching
  • Kidney disease

Evaluation of medication effectiveness:

Loratadine is a second era antihistamine and is utilized to oversee side effects of hypersensitive rhinitis, wheal arrangement, urticaria, and other unfavorably susceptible dermatologic conditions.

Like other second era antihistamines, loratadine is specific for fringe H1 receptors. Loratadine doesn't infiltrate viably into the focal sensory system and has poor liking for CNS H1-receptors. These characteristics bring about an absence of CNS depressant impacts, for example, sluggishness, sedation, and debilitated psychomotor capacity.

Nursing interventions:

  • Check the 10 medication rights
  • check for any allergies
  • Check for doctor’s order
  • Pre education about the drug
  • Administer the drug
  • Observe the client for any immediate side effects

Health education:

Educate on:

  • Drug purpose
  • timing
  • dose
  • timing
  • interactions
  • precautions
  • overdose
  • preservation/storage
  • side effects
  • complications
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