Problem

(Open-ended problem) You may have to look up/guess/vary some of the constants. If methanol...

(Open-ended problem) You may have to look up/guess/vary some of the constants. If methanol is ingested, it can be metabolized to formaldehyde, which can cause blindness if the formaldehyde reaches a concentration of 0.16 g/dm3 of fluid in the body. A concentration of 0.75 g/dm3 will be lethal. After all the methanol has been removed from the stomach, the primary treatment is to inject ethanol intravenously to tie up (competitive inhibition) the enzyme alcohol dehydrogenase (ADH) so that methanol is not converted to formaldehyde and is eliminated from the body through the kidney and bladder (k7). We will assume as a first approximation that the body is a well-mixed CSTR of 40 dm3 (total body fluid). In Section 7.5, we applied a more rigorous model.

The following reaction scheme can be applied to the body.

The complete data set for this reaction is given on the CD-ROM, P7-25 and the open-ended problem H.10. After running the base case, vary the parameters and describe what you find.

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Solutions For Problems in Chapter 7