Problem

Solutions For An Introduction to Genetic Analysis Chapter 7 Problem 3P

Step-by-Step Solution

Solution 1

a) The deoxyribonucleic acid (DNA) polymerase I enzyme was found filling the gaps in the Okazaki fragments in the lagging strand in a DNA replication.

b) This DNA polymerase III is found in the leading stand and hence it does not require any primers to initiate its polymerization reaction like the one at the lagging stand. The helicase enzyme is essential in unwinding the DNA double strands and the β Clamp that encircles the DNA like donut and keeps the enzyme polymerase III attached to the DNA molecule.

c) This DNA polymerase III is found in the lagging stand of the DNA in a replication fork. It requires the essentialities of the β Clamp, helicase enzyme as it is for the other DNA polymerase III that is working in the leading stand. In addition to these, it also requires the primase and ssb proteins. The primase enzyme is required in the lagging stand mainly to supply the requisite primers for the DNA polymerase III to act and grow the stand in the lagging stand. The function of the ssb proteins is to ensure that the unwound DNA is kept stabilized until the replication fork moves forward.

Add your Solution
Textbook Solutions and Answers Search
Solutions For Problems in Chapter 7