Problem

Solutions For An Introduction to Genetic Analysis Chapter 18 Problem 42P

Step-by-Step Solution

Solution 1

In a population, a locus has two alleles A and a. They have frequencies of p and q respectively. The relative genotypic fitnesses are shown in the table below:

Genotype

A/A

A/a

a/a

Relative fitness

1–s

1

1–g

In this population, we see the case of over dominance where heterozygotes have the highest fitness value of 1. Selection against the homozygous AA is s and against homozygous recessive aa is g.

a) If the mean fitness of allele A is equal to the fitness of allele a, then the equilibrium frequency of the allele would be:

The fitness can be calculated as:

b) When the value of s is 0.2 and g is 0.8:

Therefore, the value for p is 0.8.

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Solutions For Problems in Chapter 18