Three genotypes are present in a population. They are A/A, A/a, and a/a. The relative fitness for these three genotypes is:
• wA/A = 1.0
• wA/a = 1.0
• wa/a = 0.7
a) If the population starts at the allele frequency of p = 0.5, the value of p in the next generation can be done by selecting against the recessive allele.
Substituting the values:
b) The predicted equilibrium allele frequency if the rate of mutation is 2 x 10-5 from A to a can be calculated in this way:
Substituting the values: