Solutions For An Introduction to Genetic Analysis Chapter 18 Problem 35P

631190-18-35P AID: 2498 | 24/12/2015

a.

In the present generation, the estimated linkage disequilibrium (LD) value D₀

b.

D1 will be a value of LD in the next generation with 0.25 recombination rate:

Thus, if recombination takes place then the value of D declines.

c.

The expected frequency of the Ab haplotype is,

A = 0.50

b = 0.50

D ₀ = Observed frequencies of the Ab haplotype - expected frequencies of the Ab haplotype.

D ₁ = 0.05 (after 1 generation of recombination).

The expected frequency of Ab is 0.25 and the D₁ is 0.05