Yes, there are similarities between the DNA (deoxyribonucleic acid) replication bubbles and the transcription bubbles found in eukaryotes. They are as follows:
1. Both require large, multi-subunit machinery – replisome in replication bubble and RNA polymerase II in transcription bubble.
2. Both require helicase activity at the fork of the bubble to unwind or separate the DNA double-strands by breaking the hydrogen bonds between the complimentary bases.