Question

What additional evidence for improving clinical outcomes is introduced by analytical modeling that is not included in clinical guidelines that are based on a high level of evidence from clinical trials?

Answer 1

The evidence for improving clinical outcomes is introduced by analytical modeling that is not included in clinical guidelines is "Evidence based medicine".

Currently,it is impossible to ignore evidence based medicine in modern health care,it is a concept which relies on: i.e,individual clinical expertise, values and desire of the patients disease condition and providing best evidence medicine.

Reasons for practice of evidence based medicine in clinical guidelines:

• It helps the clinician or physicians to stay current on standardized treatment with medical practice and evidence based protocols.
• Health care providers has a better access the clinical data and get more knowledge because of improved technology such as electronic health record and to make care decision.to built protocols.With the improved access to health care data,health care providers can use evidence based medicine.
• Evidence based medicine can improve transparency,high quality and safe care at low cost.Industry can achieve goals by practicing evidence based health care and increase accountability by justifying the decision based on valid information to get better outcome.
• Evidence based medicine can improve the quality of care.

Steps for Evidence based Medicine:

• Formulation of question: Intervention,Comparison,outcomes of interest.
• Finding the best evidence: Hierarchy level provide can provide evidence to the clinical questions.
• Critical appraisal of the evidence
• Applying the evidence to the treatment of patients.

Types of studies to answer clinical questions:

Types of Clinical       questions	Type of Study
Therapy	Systematic review, Randomized controlled trail,meta analysis
Diagnosis	Controlled trails,Systematic review
Etiology	Cohort studies
Prevention	Cohort studies,Randomized controlled trails
Quality of life	Qualitative study
Cost effectiveness	Economic evaluation