Homework Answers
Ordered dose of Drug A is 200mg /day
Average steady state concentration (Cp ) is 1mg / L
What is the average amount (mg ) in the body at steady state ?
Half life of Drug A - 12hours
Volume of distribution - 130L
Bioavailability - 0.9
At steady state , rate of drug administration = rate of drug elemination
Vd = AMOUNT of drug in the body /concentration in plasma (Cp)
130L = amount of drug in the body ÷1 mg/L
Amount of drug in the body = 130L × 1 mg/L
= 130 mg of drug will be present at steady state .
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YOU ONLY NEED TO ANSWER QUESTIONS 1,5, & 8
AND…in addition to answering each question, state 2 other
questions after each of these that might be asked of you by a
health professional that would call on you to do the same
calculation, or know the same concept. Give answer for these, and
show all work.
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YOU ONLY NEED TO ANSWER QUESTIONS 1,5, & 8
AND…in addition to answering each question, state 2 other
questions after each of these that might be asked of you by a
health professional that would call on you to do the same
calculation, or know the same concept. Give answer for these, and
show all work.
174 Chapter LEARNING QUESTIONS (1) Gentamicin has an average elimination half- life of approximately 2 hours and an apparent volume of distribution of 20%...
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