Question

Below is a list of hypothetical genes with the indicated function. Which genes could be classified...

Below is a list of hypothetical genes with the indicated function. Which genes could be classified as a tumor suppressor?

(a) Gene A: Promotes Apoptosis

(b) Gene B: Inhibits Cell Cycle

(c) Gene C: Promotes Cellular Differentiation

(d) Gene D: Extends Chromosome Ends During Cell Division

(e) Gene E: Promotes Angiogenesis

(f) Gene F: Inhibits Angiogenesis

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Answer #1

Tumour suppressor genes do not allow the cell growth and differentiation in an uncontrolled way. Whereas, the oncogenes allow uncontrolled cell division.

(a) Gene A: Promotes Apoptosis ----> Tumour suppressor

(b) Gene B: Inhibits Cell Cycle ------> Tumour suppressor

(c) Gene C: Promotes Cellular Differentiation ----> Oncogenic

(d) Gene D: Extends Chromosome Ends During Cell Division ----> Oncogenic

(e) Gene E: Promotes Angiogenesis ----> Oncogenic

(f) Gene F: Inhibits Angiogenesis ----> Tumour suppressor

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