What is the name of the protein that is involved in the extra-toed mutation in cats?
A. keratin
B. double digit
C. sonic hedgehog
D. tropomyosin
ANSWER: C) Sonic hedgehog
Sonic hedgehog is involved in the extra-toed mutation in cats as the mutation occures in ZRS (genetic enhancer) regulates the expression in sonic hedgehog. Sonic hedgehod protein is used in limbs and digits as the signalling molecules.
What is the name of the protein that is involved in the extra-toed mutation in cats?...
A mutation in the gene for a particular protein gives rise to the disease osteogenesis imperfecta. Answer (and explain) the following five questions in one sentence each. What is the name of the protein? What is the mutation in this protein? Describe the structure of this protein. Why does this mutation disrupt the structure of the protein? Will taking extra Vitamin C help cure osteogeneis imperfect? Why or why not?
A ________ mutation results in no change in the protein product. mutation results in no change in the protein product O O O A silent B. nonsense C. missense D. non functional .
What would you expect to happen to a newly synthesized soluble protein if a mutation caused the deletion of the KDEL sequence? a. The protein would be returned to the ER in COPI-coated vesicles. b. The protein will be carried forward through the Golgi apparatus. c. The protein will be trapped in COPII vesicles . d. The protein will be incorporated into COPI vesicles. e. The protein will be recognized by KDEL receptors and a retrieval sequence (KDEL sequence) will...
29. Differentiate between the four possible levels of a protein. Include the bonds involved and what part(s) of the amino acid are involved. a. Primary structure b. Secondary structure c. Tertiary structure d. Quaternary structure
If there is a mutation in the gene for collagen, such as the one involved in Ehlers-Danlos syndrome, and the individual produces defective collagen, how would it affect coagulation? a. The syndrome affects the clotting factors and platelet aggregation. b. The syndrome leads to hyper-coagulation of blood. c. Coagulation is not affected because collagen is not required for coagulation. d. The syndrome occurs due to the breakdown of platelets.
The gene encoding protein Bog in E. coli has been changed by a point mutation in its open reading frame. Originally the gene encoded a 108 amino acid long functioning protein whose amino acid composition favored nonpolar and negatively charged amino acids. After the mutation it encodes a 110 amino acid long non-functioning protein that is now rich in polar uncharged amino acids and positively charged amino acids. Which mutation scenario best explains this observation. A) A frame-shift caused by...
Name the two different types/classes of mutations. What are the possible outcomes of a point substitution mutation? What is meant by a "degenerate" or "redundant" genetic code? How might this protect against erroneous protein production? What are the two steps in protein synthesis. What type(s) of nucleic acid are involved in each step. Why is protein synthesis important? What is an enzyme and why is it important?
Genetic Code: The dictionary of the language of life Use the Genetic Code as a "dictionary" to solve the exercises on next page 5. If a mutation happens in the DNA that changes the T at base 14 to a G: a) What would be mutated sequence of nucleotides in the corresponding codon in the mRNA and the anticodon in the tRNA? Is there any change in the corresponding amino acid in the protein? b) What is the name of this type of...
The 2 types of mutation are: _______________________________ and _________________________________ a. Base mutation and chromosomal mutation b. Point mutation and base substitution c. Duplication and translation d. Frame shift and insertion 2. What is the anticodon on tRNA that corresponds to the mRNA codon 5’-GUA-3’? 3’-CAU-5’ 5’-CAU-3’ 3’-CAT-5’ 5’-AUG-3’ 3..Which below will end up being expressed in the protein? Exons Terminators Introns Promoters
Gene Mutation Worksheet 1. There are several types of gene mutations. (a) List two. (b) What do they have in common? (c) How are they different? 2. A geneticist found that a particular DNA mutation had no effect on the protein coded by a gene. What kind of mutation was this? Why? 3. (a) Name one amino acid that has more than one codon. (b) Name an amino acid that has only one codon 4. Look at the following sequence:...