Question

(4 pts) The human MN blood type is determined by two codominant alleles, LM and LN The frequency of LM in Eskimos on a small Arctic island is 0.80. 6. a. If random mating takes place in this population, what are the expected frequencies of the M, MN, and N blood types on the island? b. If the inbreeding coefficient for this population is 0.05, what are the expected frequencies of the M, MN, and N blood types on the island?

Answer 1

answer: According question expected frequencies of the M, MN, and N blood types on the island

f (L^M) = p = 0.80, then f (L^N) = q = 1-p = (1 - 0.80) = 0.20

frequency of (L^M L^M) = p² + Fpq = (0.80)² + 0.05 (0.80) (0.20) = 0.64 + 0.008 = 0.648

frequency of (L^M L^N) = 2pq - 2 Fpq = 2 (0.80) (0.20) - 2 (0.05) (0.80) (0.20) = 0.2 - 0.016 = 0.304

frequency of ( L^N L^N) = q ²+ Fpq = (0.20)² + 0.05 (0.80) (0.20) = 0.04 + 0.008 = 0.048