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Solutions For An Introduction to Genetic Analysis Chapter 10 Problem 13P

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Solution 1
a) Recombinant DNA molecules are the sequences that results from the molecular cloning. The recombination takes place during the development of new combination of alleles. It occurs by pairing the homologous chromosomes through the breakage and rejoining of DNA strands to produce new DNA molecules. Recombination is a general method of DNA repair in both eukaryotes and bacteria.

b) The term recombinant frequency is also called as crossing over rate, which is the percentage of recombinant gametes prepared by crossing over. Recombinant constantly refers to two genes situated in the same chromosome. The genes with recombination frequency differ with the distance between the genes in the chromosome because the farther the distance among the loci of two genes in a chromosome, the higher the recombination frequency among these genes.

The recombination can takes place with a little chance at any site along the chromosome, but the frequency of recombination between two locations depends on the distance.

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