At pH 7 the measured Michaelis constant and maximum velocity for the enzymatic conversion...

At pH 7 the measured Michaelis constant and maximum velocity for the enzymatic conversion of fumarate to L-malate,

are 4.0 X 10-6 M and 1.3 X 10-3 [E]0 s-1, respectively, where [E]0 is the total molar concentration of the enzyme. The Michaelis constant and maximum velocity for the reverse reaction are 1.0 X 10-5 M and 800 [E]0 s-1, respectively. What is the equilibrium constant for the hydration reaction? (The activity of water is set equal to unity; see chapter 4.)