Question

Hemophilia A is a kind of genetic deficiency. It is suggested that fruit flies are used as experimental models, please explain how can the fruit flies give evidence about the gene function as well as what kind of mutated gene exist leading to the disease. There is a words limit, please write more than 450 words , but less than 800 words.

Answer 1

Not only hemophilia for most of genetic diseases fruit flies used as model organisms. Since it contains a simple genome and genes of genetic diseases about (60-75)% present in fruit fly. It helps to determine the mutation and expression.

Homologus genes present in fruit flies as in humans are mutated as in genetic mutation of humans. For therapeutic purpose and drug discovery, these flies are used for model which is mutated. And the drugs to be tested are performed in these flies. For to see the reaction and adverse effect of drugs.