How can poisons alter cell signaling? Give an example.
Answer :- An important aspect of host-pathogen systems is the mechanism by which toxins secreted by many pathogenic organisms change the signaling events by associating them with host cell receptors to increase cellular cAMP concentrations, resulting in aberrant activity or death of cells.
The molecular mechanism underlying a toxin interaction with a signaling cascade is directed towards a specific target on the cell membrane where a normal physiological reaction is triggered by standard signals or second messengers. Certain toxins act as pores that interfere with the intracellular ionic equilibrium and collapse.
Dermal Toxicity may occur when a toxicant reaches direct contact with or is internally transmitted to the skin. Effects range from mild discomfort to serious changes including irreversible damage, hypersensitivity, and skin cancer.
Give one example of a ligand-receptor pair for each of the six generic types of cell signaling. Do not include the details of the pathway, just give its name and how/why it is important to the cell. Line up the six generic types, using the generix names, according to soeed of the signaling process and give an explanation of the order that you determined. I'm guessing the six types are: GCPR Receptor Tyrosine Kinase Receptor Guanylyl Cyclase Adhesion receptor (integrin)...
Q1: A. Find an example of bacteria that communicate and how do they communicate? B. give examples of cell communication in the human body. For each example identify the following components of the signaling pathway: signal, receptor, messengers, output effects
difference between local and long distance signaling in cells give an example of each
. . Colchicine can be used to alter the chromosome content of a cell by disrupting chromosome disjunction and cell division (an exposed cell would enter mitosis but fail to divide). After treatment with colchicine, the altered chromosome content would make the cell autopolyploid triploid aneuploid allopolyploid
How does protein modification play a role in cell signaling? Provide three examples.
9a) To determine if the change in localization of EGFR impacts on the cell signaling outcomes how could you prevent this from occurring? b) To determine if the turnover of EGFR impacts on the cell signaling outcomes how could you prevent this from occurring?
Explain the Cell Signaling Analysis.
2) Consider the picture of SRT1720 shown below (SRT1720 was originally designed to alter Sirtuin signaling), and answer the following questions: a) Which of the groups in red has the most acidic hydrogen? (2 pts) NH NH b) Which of the groups in red has the most basic lone pair of electrons? (2 pts) How can you make this C-N bond? c) Draw a reaction (starting materials, mechanism, and products) that would let you create the bond shown in the...
Problem Five One of the transducers in many growth factor signaling cascades is ras. a) How can mutations in ras (found in some types of cancers) contribute to transforming a normal cell into a tumor cell? b) Describe how ras plays a role in MAPK signaling pathways.
-regulation is used to describe the "turning on" of protein synthesis by cell signaling. 38. The term on a. b. up forward c. d. start 39. The three steps of protein synthesis, in the correct order from left to right, are: translation, transcription, and cell signaling. transcription, translation, and cell signaling. cell signaling, transcription, and translation. cell signaling, translation, and transcription a. b. c. d. the protein. 40. You are making a scrambled egg for breakfast. When you heat the...