techniques used for screening mutations on STag2 gene? things like splicing, sequencing , etc.
techniques used for screening mutations on STag2 gene? things like splicing, sequencing , etc.
Homework Answers
STAG2 gene codes for a multimeric cohesion complex, which is required for regulating sister chromatid separation during mitosis. Inactivation of STAG2 will result in an increased number of abnormal mitotic events while mutational correction of STAG2 mutations enhanced the chromosomal stability.
Inactivating mutations in the STAG2 gene have been reported in low frequency in several cancers. which were found by nonsense, frameshift and splicing techniques and in few cases missense mutations of unknown significance were also identified. Inactivate the STAG2 mutation also results in low tumor frequency.
In a few cancer cases, next-generation sequencing was also used for screening the mutation in the STAG2 gene by the scientist, but no mutations were reported.
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techniques used for screening mutations on STag2 gene? things
like splicing, sequencing , etc.
A map is shown below for a gene that uses alternative splicing. 5 splice sites are...
A map is shown below for a gene that uses alternative splicing. 5 splice sites are indicated with a 5, while 3 splice sites are indicated with a 3. Boxes below the gene are used to represent the presence of sequence elements found in the pre-mRNA for this gene. Splicing enhancers are shown as filled boxes, while splicing silencers are shown as stippled boxes. The enhancers and silencers only act on the splice site that they overlap (eg., the stippled...
Which of the following techniques could be used to accurately and precisely quantify gene expression? Select...
Which of the following techniques could be used to accurately and precisely quantify gene expression? Select all that apply. ORNA - Sequencing O RNA in situ hybridization ODNA microarray ORT-PCR OqRT-PCR
why isn’t gene sequencing and genomic sequencing normally used to identify pathogens? Why can antibody testing...
why isn’t gene sequencing and genomic sequencing normally used to identify pathogens? Why can antibody testing of patient serum be inaccurate? What does MacConkey agar detect? How is gelatinase tested for? How is a positive gelatinase test determined? How is the oxidase test performed?
why us ur that some gene mutations can have drastic effects in ones phrnotype ( like...
why us ur that some gene mutations can have drastic effects in ones phrnotype ( like death ir debilitating dusease) while ktber mutations no effect on the phenotype whatsoever?
Drosophila embryos with null mutations in the proboscipedia gene have their proboscis, a structure used in...
Drosophila embryos with null mutations in the proboscipedia gene have their proboscis, a structure used in feeding, replaced with legs. Given this phenotype, what type of developmental gene is proboscipedia likely to be? Gap Segment polarity Homeotic Pair-rule Maternal effect
help me please How are gene editing techniques used for gene therapy Define regenerative medicine and...
help me please How are gene editing techniques used for gene therapy Define regenerative medicine and provide examples of how cell and tissue transplantation and organ engineering can be used Define and discuss a role for three-dimensional bio printing, engineering organoids and organs-on-chips
7.. In the controlled termination method of DNA sequencing, reading the gel from _____ gives the...
7.. In the controlled termination method of DNA sequencing, reading the gel from _____ gives the sequence in the _____ direction; _____ fragments that were terminated _____ in polymerization move faster down the gel a. bottom to top; 5′ to 3′; shorter; early b. top to bottom; 5′ to 3′; longer; early c. bottom to top; 5′ to 3′; longer; later d. top to bottom; 5′ to 3′; shorter; early e. bottom to top; 3′ to 5′; shorter; early 8....
All cells in a mouse are genetically identical, yet many cells like brain or liver cells...
All cells in a mouse are genetically identical, yet many cells like brain or liver cells perform specialized functions. How do these cells achieve this level of specialization? a. Through transcription factor activity b. Through alternative splicing of mRNA c. Through the accumulation of mutations d. Through gene silencing e. Through post-translational modifications Which material would not be required for determining the sequence of a 400 bp DNA fragment by the high-throughput sequencing method? a. A short, artificially synthesized primer...
13) The number of new mutations in a given gene per cell generation is called? B)...
13) The number of new mutations in a given gene per cell generation is called? B) mutation rate C) recombination frequeney 14) A type of spontaneous mutation that occur when a purine base is removed from the DNA is A) deamination D) alkylate bases В) apurination E) base analog C) thymine dimers 15) A type of spontaneous mutation that involves a temporary change in the base conformation because the keto group may change to an enol functional group or amino...
B12030 (12) Defining the gene E cow mutants are isolated that cannot utilize tetrahydro-cannabinol (THC) as...
B12030 (12) Defining the gene E cow mutants are isolated that cannot utilize tetrahydro-cannabinol (THC) as a source of carton. energy or anything else. The map positions in minutes of the the mutations are 18 minutes #2.4 5.0.7. 10, 11, 12, 13]. [42 minutes. M 1: 151 minutes: 391: 166 minutes: #8: (85 minutes: #141 fa) What is the minimum number of genes involved in THC utilization? OVA. AM 2 5 6 7 10 11 12 13 4 0 0...
A map is shown below for a gene that uses alternative splicing. 5 splice sites are indicated with a 5, while 3 splice sites are indicated with a 3. Boxes below the gene are used to represent the presence of sequence elements found in the pre-mRNA for this gene. Splicing enhancers are shown as filled boxes, while splicing silencers are shown as stippled boxes. The enhancers and silencers only act on the splice site that they overlap (eg., the stippled...
Which of the following techniques could be used to accurately and precisely quantify gene expression? Select all that apply. ORNA - Sequencing O RNA in situ hybridization ODNA microarray ORT-PCR OqRT-PCR
Drosophila embryos with null mutations in the proboscipedia gene have their proboscis, a structure used in feeding, replaced with legs. Given this phenotype, what type of developmental gene is proboscipedia likely to be? Gap Segment polarity Homeotic Pair-rule Maternal effect
All cells in a mouse are genetically identical, yet many cells like brain or liver cells perform specialized functions. How do these cells achieve this level of specialization? a. Through transcription factor activity b. Through alternative splicing of mRNA c. Through the accumulation of mutations d. Through gene silencing e. Through post-translational modifications Which material would not be required for determining the sequence of a 400 bp DNA fragment by the high-throughput sequencing method? a. A short, artificially synthesized primer...
13) The number of new mutations in a given gene per cell generation is called? B) mutation rate C) recombination frequeney 14) A type of spontaneous mutation that occur when a purine base is removed from the DNA is A) deamination D) alkylate bases В) apurination E) base analog C) thymine dimers 15) A type of spontaneous mutation that involves a temporary change in the base conformation because the keto group may change to an enol functional group or amino...
B12030 (12) Defining the gene E cow mutants are isolated that cannot utilize tetrahydro-cannabinol (THC) as a source of carton. energy or anything else. The map positions in minutes of the the mutations are 18 minutes #2.4 5.0.7. 10, 11, 12, 13]. [42 minutes. M 1: 151 minutes: 391: 166 minutes: #8: (85 minutes: #141 fa) What is the minimum number of genes involved in THC utilization? OVA. AM 2 5 6 7 10 11 12 13 4 0 0...
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