Consider a cell at T = 310 K with the following ionic conditions: [K+]in = 130 mM, [Na+]in = 14 mM, [Ca2+]in = 1.2 mM; [K+]out = 4 mM, [Na+]out = 140 mM, [Ca2+]out = 1.2x10-4 mM. Part B: if the membrane conducts only these 3 ions, and gNa=gCa=0.10gK at rest, what is the resting membrane potential?
We have been given the value of conductance rather than the permeability , which is generally used in the calculation of the membrane potential .
Conductance measures the movement of charge across the membrane.
Permeability measures the
capability of ions to flow across the membrane, regardless of
whether they are moving across the
membrane.
This means that tha conductance is also directly propotional to the permeability.
We are given that gNa = gCa = 0.10 gK
This means the permeability will also be
pNa = pCa = 0.10 pK.
Consider a cell at T = 310 K with the following ionic conditions: [K+]in = 130...
Given these parameters, what is the AG for K ion transport into the frog muscle cell in the presence of Ach? Dr. Knowsalot smiles and nods. "Good," she says. "Now let's see whether K+ ions pass through the open Ach receptors into the cell. As you might remember, these channels are permeable to Na+, K+, and Ca2+. For a typical frog muscle cell, the concentration of K+ is roughly 124 mM inside the cell and 2.30 mM outside the cell."...
1. Animal cells have a Na,K pump that couples the energy of ATP hydrolysis to transport 3 Na ions out of the cell and 2 K ions into the cell. Inside astrocytes, the concentration of Na is 20 mM and the concentration of K is 130 mM. The extracellular concentrations of Na and K are 145 mM and 5 mM, respectively. Calculate the energy required for the transport of Na and K , with this stoichiometry; assume that the cell...
(a) For the following conditions, calculate the change in the Gibbs energy associated with transporting 1 mole of sodium ions from inside to outside the cell. Is work required or produced? Outside: [Na+] = 130 mM [K+] 5 mM Electrical potential = 0 mV [Na+]= [K 110 mM Electrical potential =-70 mV Temperature 25 °C Inside: 10 mM (b) For the same conditions, calculate the change in the Gibbs energy associated with transporting 1 mole of potassium ions from outside...
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Question 4 2 pts During and action potential, sodium (Na+) rushes into the cell causing of the cell. Then sodium channels close and potassium (K+) rushes out of the cell, causing of the cell. However, the potassium overshoots and causes Question 5 2 pts During the refractory period, the pumps Na+ ions out of the cell and K+ions into the cell, re-establishing the resting membrane potential and concentration gradient. Serotonin Acetylcholine Glutamate Endorphins Barbiturates GABA Dopamine Cocaine Sodium Potassium Calcium...
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Question 1. The following questions are based on the information below, from a mutated nerve cell in the brain: I nterstitial fluid intracellular fluid Na+ 5mM 180mM K+ 15mM 100mM Ca2+ 300mM 6mM Cl- 105mM 15mM 1) Calculate the equilibrium potentials for each ion. 2) From those values, predict the transport mechanism for each ion. 3) Which two ions are involved in establishing the resting potential? 4) Of those two ions, which has the greater permeability? 5) Which ion is...
Consider the following for problems 1 through 5: The concept of electric potential difference plays an important role in the human nervous system. A nervous impulse, for example, is an action potential that results from the temporal rising and lowering of the cell membrane potential, which in turn is caused by the equally temporal influx of sodium (Na+) ions into the cell. The sodium ions enter the cell through Hodgkin-Huxley channels, named after English physiologist/biophysicists Alan Hodgkin and Andrew Huxley....
*** I need help with PART F of
this problem. Hints are given in other parts of the problem and all
information available is given on the worksheet. Please help, thank
you!
The post-synaptic cell at a chemical synapse has the following distribution of ions between the cytosol and the extracellular environment. Consider that the relative permeabilities for Na, K and Cl' are 1, 100 and 50, and that there are no other significant permeabilities, lon Concentration (in mM) Extracellular...