Biochem: what would happen to blood biotin levels if the deficiency was in the holocarboxylase synthetase?
Homework Answers
Mammalian organisms retains enzyme set called holocarboxylase synthatase for metabolism of fatty acids.
holocarboxylase synthatase
Biotin + different apocarboxylases-------------------> biotin attachment with ε-amino group of lysine of protein enzyme apocarboxylase activating them for fatty acid metabolism then biotin attached to protein is regenrated by proteolytic degration and bionitidase
If holocarboxylase synthatase is defective, biotin will not be utilized and its level in blood will be higher.
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Biochem: what would happen to blood biotin levels if the deficiency
was in the holocarboxylase synthetase?
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