In the case of the gene that codes for sickle-cell anemia, a very dry climate would have a selective advantage for:
A. heterozygotes and homozygotes for the sickle-cell allele.
B. homozygotes for the wild-type allele.
C. homozygotes for the sickle-cell allele.
D. homozygotes for the wild-type allele and homozygotes for the sickle-cell allele.
E. heterozygotes.
The sickle cell anemia give advantage from malaria disease. But in dry climate, mosquitoes are scarce and so is the malaria. So the sickle cell condition has no advantage there. Even the heterozygote have slightly sickle RBCs and hence they are also not advantageous. Hence answer is option B. Homozygotes for wild type allele.
In the case of the gene that codes for sickle-cell anemia, a very dry climate would...
A mutation in one of the hemoglobin genes causes sickle cell anemia. The sickle cell allele, S, severely reduces fitness in people who are homozygotes, SS. In contrast, people with at least one normal hemoglobin allele, A, do not suffer the effects of sickle cell anemia, even if the individual is a heterozygote, AS. Interestingly, though, in areas with a high rate of malaria, heterozygotes that carry the sickle cell allele have a higher fitness than do individuals that are...
Sickle-cell anaemia is an example of how fitness depends on environmental conditions. In places where malaria, caused by Plasmodium falciparum is common, HbAHbS heterozygotes have a selective advantage compared to individuals who are homozygotes for the wild type allele. However, HbSHbS homozygotes suffer from sickle-cell anaemia and usually die before producing offspring. The relative fitness (w) of the three genotypes in Nigeria are: HbAHbA 0.78, HbAHbS 1.0 HbSHbS 0.07 a. What is the mathematical relationship between relative fitness and selection...
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explain, in detail, the relationship between malaria and sickle-cell anemia. Why is having one sickle-cell allele considered a selective advantage? Is this equally beneficial for someone who is homozygous recessive for sickle-cell? Why or why not? Note: use specific vocabulary to describe your answers (genotype, homozygous d, homozygous r, natural selection, heterozygous, etc)
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The sickle cell anemia allele is very common for a harmful mutation. Why? (in-depth answer pls)
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