Question A patient was presented with suspected salicylic acid (SA) overdose. The initial plasma concentration of...
Question
A patient was presented with suspected salicylic acid (SA) overdose. The initial plasma concentration of SA was 2000 mg/L and 1 hour later it is 1000 mg/L.
a) What is the half-life of SA in this patient? (2)
b) Calculate the elimination constant of SA in this patient. (4)
c) Calculate how many hours will be needed for the SA to reach a level of 62.5 mg/L if the kel = 0.693 in this patient. (answer 5 hours) (4)
You may find the following equations useful: LogCt = Log Co – (kel X t)/2.303; Half-life (t1/2) = 0.693/kel; Vd = dose (mg) / plasma concentration (mg/L); % Bioavailability = (AUCoral/AUCiv)x100 Vd = Dose i.v. / (AUC x kel)
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A patient was presented with suspected salicylic acid (SA)
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Please show work.
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DO NOT ANSWER QUESTION 10. I only need question 9 and 11
plz, answer all questions clearly and correctly. i am begging
you
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