Step-by-Step Solution
a.
The frequencies of double transformants are compared to determine, which genes are closely linked. The tightly linked genes are A, C, and D. Whenever B is involved, pair wise testing gives low values, but fairly high rates when any drug but B is involved. Thus, this suggests that the 
resistance is quite distant from the other three genes.
b.
The frequencies of double and triple transformants are compared to determine the relative order of genes for resistance to A, C, and D. The frequency of resistance to AC is approximately the same as the frequency of resistance to ACD. This strongly suggests that D is in the middle. Also, the frequency of AD co-resistance is higher than AC, this suggests that the gene for A resistance is closer to D than to C, and the frequency of CD is higher than AC, which suggests that
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