Some mutations in the tra gene of Drosophila cause XX females to appear as males. In contrast, other mutations in tra cause XY male flies to appear as normal females. Which of these phenotypes would you expect if a mutation in tra resulted in a null allele? Which would you expect if the mutation produced a constitutively active tra gene product?
¦ H I NT: This problem involves an understanding of the SXL pathway in Drosophila. The key to its solution is to review the functions of the normal TRA protein in Drosophila males and females.
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