Nucleotide analogs cause frameshift mutations.True or false
Nucleotide analogs cause frameshift mutations.True or false
Homework Answers
Ans. True.
The freamshift mutation is the genetic alteration or mutation which occurs due to the deletion or insertion in a DNA sequence that shifts the way the sequence is read. The DNA sequesnces are made of small molecule chains, these small molecules are called nucleotides or nucleotide analogs. So any change in the nucleotides will lead to frameshift mutation.
QUESTION 3 In a "frameshift" mutation O a the mutation is not in DNA. the nucleotide...
QUESTION 3 In a "frameshift" mutation O a the mutation is not in DNA. the nucleotide that mutates causes a stop codon to occur instead of the placement of an amino acid. c. addition or deletion of one or two nucleotides causes the codons to be off pattern and therefore the mutation. 4. the nucleotide that mutates causes no change in the amino acid specified.
What is the mechanism by which base analogs cause mutations? A. Deamination of cytosine leading to...
What is the mechanism by which base analogs cause mutations? A. Deamination of cytosine leading to uracil B. Intercalating between adjacent bases in DNA C. Oxidation of guanine Mispairing with normal bases D. Depurination of guanines
Pick the statement about mutation that is false.
Pick the statement about mutation that is false. Intercalating agents cause frameshift mutations. Gain-of-function mutations are usually recessive. The Ames test measures reversion frequencies. Depruination of a nucleotide can happen spontaneously. Tandem duplications can be generated by strand slippage during replication.
Sovaldi is a nucleotide analog (sometimes called a “nuke”). What nucleotide is it most similar to?...
Sovaldi is a nucleotide analog (sometimes called a “nuke”). What nucleotide is it most similar to? Can you find the structures of some other nukes and which nucleotides are they analogs of?
5'-ATG-TCC-TCG-AAT-TTT-CCC-3' if a student induces a 2-nucleotide deletion to this sequence resulting in a frameshift mutation,...
5'-ATG-TCC-TCG-AAT-TTT-CCC-3' if a student induces a 2-nucleotide deletion to this sequence resulting in a frameshift mutation, changing the 3rd through 5th amino acids to Glu Phe Ser, what two nucleotides were deleted?
Ionizing radiation and oxidative damage can cause DNA double-strand breaks. A. True. B False Nucleotide Excision...
Ionizing radiation and oxidative damage can cause DNA double-strand breaks. A. True. B False Nucleotide Excision Repair involves recognition of distortions in the DNA double helix rather than specific base changes. A. True. B False Homologous recombination does not occur in prokaryotic cells. A. True. B False Many chemotherapeutic agents are paradoxically DNA damaging agents A. True. B False Meiot.c recombination starts with, double-strand break caused by errors In DNA replication A. True. B False ONA replication origins are typically...
1. Indicate which type of physical mutations (nonsense, missense-nonsynonymous, missense-synonymous, silent, polymorphism, frameshift) cause the following...
1. Indicate which type of physical mutations (nonsense, missense-nonsynonymous, missense-synonymous, silent, polymorphism, frameshift) cause the following results: A. Hypomorph B. Amorph C. Hypermorph
Question Two (Five Parts): A. The drugs in HAART are: two nucleoside analogs and one protease...
Question Two (Five Parts): A. The drugs in HAART are: two nucleoside analogs and one protease inhibitor II. three nucleoside analogs and one protease inhibitor III. two nucleoside analogs and two protease inhibitor IV. three nucleoside analogs and four protease inhibitor B. Decreased risk of HIV transmission is a benefit of adherence True Il. False C. Fear of disclosing one's HIV-positive status to others is not a factor effecting medication adherence True Il. False D. Which of the following is/are...
Mutagens: Chemical mutagens: Nitrous acid: Nucleoside analogs: Benzopyrene: Aflatoxin: Acridine dyes: Radiation: X-rays and gamma rays:...
Mutagens: Chemical mutagens: Nitrous acid: Nucleoside analogs: Benzopyrene: Aflatoxin: Acridine dyes: Radiation: X-rays and gamma rays: Ultraviolet rays: Repair of UV induced damage: Photolyases: Nucleotide excision repair: Methylases: Xeroderma Pigmentosum: Identifying Mutants: Identifying chemical carcinogens: The Ames test:
2. A single nucleotide addition and a single nucleotide deletion approximately 15 base pairs apart in...
2. A single nucleotide addition and a single nucleotide deletion approximately 15 base pairs apart in the DNA cause a protein change in sequence friom Old Phe-Ser-Pro-Arg-Leu-Asn-Ala-Val-Lys to ne Phe-Val-His-Ala-Leu-Met-Ala-Val-Lys a. What are the old and new mRNA nucleotide sequences? Old 5' uu Au b. Which nucleotide has been added? Which has been deleted?
QUESTION 3 In a "frameshift" mutation O a the mutation is not in DNA. the nucleotide that mutates causes a stop codon to occur instead of the placement of an amino acid. c. addition or deletion of one or two nucleotides causes the codons to be off pattern and therefore the mutation. 4. the nucleotide that mutates causes no change in the amino acid specified.
Ionizing radiation and oxidative damage can cause DNA double-strand breaks. A. True. B False Nucleotide Excision Repair involves recognition of distortions in the DNA double helix rather than specific base changes. A. True. B False Homologous recombination does not occur in prokaryotic cells. A. True. B False Many chemotherapeutic agents are paradoxically DNA damaging agents A. True. B False Meiot.c recombination starts with, double-strand break caused by errors In DNA replication A. True. B False ONA replication origins are typically...
Question Two (Five Parts): A. The drugs in HAART are: two nucleoside analogs and one protease inhibitor II. three nucleoside analogs and one protease inhibitor III. two nucleoside analogs and two protease inhibitor IV. three nucleoside analogs and four protease inhibitor B. Decreased risk of HIV transmission is a benefit of adherence True Il. False C. Fear of disclosing one's HIV-positive status to others is not a factor effecting medication adherence True Il. False D. Which of the following is/are...
Mutagens: Chemical mutagens: Nitrous acid: Nucleoside analogs: Benzopyrene: Aflatoxin: Acridine dyes: Radiation: X-rays and gamma rays: Ultraviolet rays: Repair of UV induced damage: Photolyases: Nucleotide excision repair: Methylases: Xeroderma Pigmentosum: Identifying Mutants: Identifying chemical carcinogens: The Ames test:
2. A single nucleotide addition and a single nucleotide deletion approximately 15 base pairs apart in the DNA cause a protein change in sequence friom Old Phe-Ser-Pro-Arg-Leu-Asn-Ala-Val-Lys to ne Phe-Val-His-Ala-Leu-Met-Ala-Val-Lys a. What are the old and new mRNA nucleotide sequences? Old 5' uu Au b. Which nucleotide has been added? Which has been deleted?
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