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Solutions For An Introduction to Genetic Analysis Chapter 14 Problem 11P

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Solution 1

Bacteria have small genomes (roughly 3 Mb pairs) and essentially no repeating sequences. Hence, the whole- genome shotgun approach would be used to sequence the genome of newly found bacterial species.

In contrast, the genomes of the bacterial sequences are easy to assemble. Bacterial DNA (deoxyribonucleic acid) is single copy DNA with no repeating sequences. Therefore, any given sequence read from a bacterial genome will come from one unique place in that genome

Similarly, contigs within bacterial genomes can often be assembled into larger contigs representing most or all of the genome sequence in a straight forward manner.

Moreover, a typical bacterial genome is only a few mega base pairs of DNA size. Recently, almost 674 bacterial genomes had been fully sequenced and many are in process.

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Solutions For Problems in Chapter 14