Solutions For An Introduction to Genetic Analysis Chapter 4 Problem 43P

a) The cross is pro his⁺ x pro⁺ his. The first tetrad class consisting of 6 members is the NPD class. The second tetrad class is the T class consisting of 82 members. The third class is PD consisting of 112 members. When PD>> NPD, it indicates that the two genes are linked.

b) The map distance can be calculated by finding the recombination frequencies:

For NPD:

For T:

The map distance can be calculated by using the recombination frequencies calculated:

The map distances can be diagrammatically represented:

c) To correct multiple crossovers the Perkins formula can be used: