Solutions For An Introduction to Genetic Analysis Chapter 2 Problem 60P

Hypophosphatemia is caused by the X-linked dominant allele. Let us consider the allele is H and normal allele is h.

Therefore, the genotype of the man with hypophosphatemia can be identified as HY and the genotype of the normal woman is hh.

Therefore, the cross between yields the progeny of the following genotypes: Hh, hY in the ratio 1:1. The Hh genotype represents the females with hypophosphatemia and the genotype, hY represents normal males.

As the sons do not inherit X-linked dominant allele from the father, the F1 progeny yields normal males. The male progeny always receive the X chromosome from their mothers. Thus, none of the sons will have hypophosphatemia.