Problem

Solutions For An Introduction to Genetic Analysis Chapter 2 Problem 61P

Step-by-Step Solution

Solution 1

Pedigree for Duchenne muscular dystrophy:

E:\Naveen\2015\H2\pic\pedi.jpg

A woman whose brother is with Duchenne muscular dystrophy is D/-. She would have inherited it from the maternal grandmother. The probability that the woman inherited d allele from her is .

The probability that the woman passes to the child is .

The probability that the child should be made is.

The probability that the woman would have a affected child is

If my mother's brother is having the disease means, my mother is the carrier of the allele. The probability of my mother receiving the allele is , and I getting that allele from my mother am .

So, the probability that I have received this allele is.

My father does not have the allele, as he is not affected by the disease. So, I cannot receive the allele from my father. If my mother is heterozygous for that allele, I may inherit the allele. As she comes into the family pedigree, unrelated, the probability of me getting the allele is nothing. Below is the pedigree:

E:\Naveen\2015\H2\pic\pedi2.jpg

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