Perhaps, it could be uncertain that the 23S rRNA (ribosomal ribonucleic acid) of prokaryotes would be able to substitute for the eukaryotic 28S rRNA, due to the dissimilar size, which involves a different folding model that would influence the affinity for protein components of 60S subunit of eukaryotes, which contains 49 proteins. In 50S subunit of prokaryotes 31 proteins are present. Therefore, the 23S rRNA to perform its function efficiently it would be capable to target an interrelated other than different set of proteins.
During the development of the ribosome for translation, the rRNA and ribosomal proteins developed as a unit and work together strongly in both prokaryotes and eukaryotes. The changes in the rRNA sizes, and number of protein components among prokaryotes and eukaryotes specify evolutionary difference in this complicated interaction.